Absolutely - Those sorts of statements undermine Hillary a great deal.
This was really well put by a Clinton delegate, as reported by Ambinder:
The issues that Hillary Clinton has worked so tirelessly for--expanded access to healthcare, a woman's right to choose, the restoration of America's standing in the world--have been just as tirelessly opposed by John McCain and the GOP. If you refuse to support Obama in November you are standing in opposition to Hillary and thwarting her lifetime of hard work.
What's more, you will irreversibly damage her entire future. At BEST, Hillary will be seen as powerless and unable exercise leadership in regard to her supporters. At WORST, she will be seen as conniving to sabotage her own party at the most crucial political moment in a generation. Either way, her career will be over.
There have been lots of polls done that break down the results by gender. Often you need to look at the full report of the poll on-line. If you do, you'll see Obama is doing very well with women overall.
I'm really glad to see that - and also glad to get the sense that our old friend Alegre criticized the McCain ad using Hillary Clinton:
Mac's latest ad using footage of Hillary stepped over a serious line. Shes a big girl and can fend for herself. She doesn't need McCain to take up her part re: BHOs veep selection. Hell, for all he knows, BHO offered it to Hillary and she turned him down.
And what a blogger disagreed with her, she pointed out that the Republicans are not the Clintons' allies or friends.